Phoenix, AZ | World’s Best Cities

Phoenix, AZ

Phoenix just keeps getting hotter – in the very best way. TSMC’s north Phoenix campus is now the largest foreign direct investment in U.S. history: after breaking ground on its third semiconductor fab in April 2025, the chipmaker paid $197 million in January 2026 for an additional 900 acres near Loop 303 and I-17, advancing a $165-billion, six-fab GigaFab cluster that cements a #16 national Innovation ranking for the long haul. ASU Health breaks ground this year at the Phoenix Bioscience Core, joining CAMI’s immunotherapy lab to anchor one of North America’s fastest-rising health-tech corridors. 

Downtown hospitality is keeping up with the 17-story Denū Hotel and Spa opening soon at Central and Adams, with 236 rooms, rooftop pool with skyline views, 22,500 square feet of event space, and Gensler-led interiors channeling the Sonoran Desert, sited within an Opportunity Zone. The forthcoming billion-dollar VAI Resort in Glendale boasts 1,100 rooms, an 11,000-seat amphitheater, and the adjacent Mattel Adventure Park. New nodes of density are emerging everywhere. The 100-acre CityNorth on Loop 101 welcomes Republic Services’ 240,000-square-foot new HQ alongside 3,400 apartments, with a dual-branded AC/Element hotel arriving in 2027. With a #11 national ranking for Nature & Parks and #12 for both Family-Friendly Attractions and Restaurants, Phoenix’s growth is as much about quality of life as it is square footage.